Welcome to IDT Biophysics

IDT Biophysics Publications

A bibliography of research papers published by the Biophysics group at IDT. Click on the reference and you will be redirected to the abstract. If available, you will be able to obtain a PDF download of the paper through the publisher site.

Owczarzy R, You Y, Groth CL, and Tataurov AV (2011) Stability and mismatch discrimination of locked nucleic acid-DNA duplexes. Biochemistry, 50:9352-9367.

You Y, Tataurov AV, and Owczarzy R (2011) Measuring thermodynamic details of DNA hybridization using fluorescence. Biopolymers, 95:472-486.

Owczarzy R, Tataurov AV, Wu Y, Manthey JA, McQuisten KA, Almabrazi HG, Pedersen KF, Lin Y, Garretson J, McEntaggart NO, Sailor CA, Dawson RB, and Peek AS (2008) IDT SciTools: a suite for analysis and design of nucleic acid oligomers. Nucleic Acids Res., 36:163-169.

Owczarzy R, Moreira BG, You Y, Behlke MA, and Walder JA (2008) Predicting stability of DNA duplexes in solutions containing magnesium and monovalent cations. Biochemistry, 47: 5336-5353.
Additional data (complete UV melting profiles)


Tataurov AV, You Y, and Owczarzy R (2008) Predicting ultraviolet spectrum of single stranded and double stranded deoxyribonucleic acids. Biophys. Chem., 133: 66-70.

You Y, Moreira BG, Behlke MA, and Owczarzy R (2006) Design of LNA probes that improve mismatch discrimination. Nucleic Acids Res., 8: 60.

Owczarzy R (2005) Melting temperatures of nucleic acids: Discrepancies in analysis. Biophys. Chem., 117: 207-215.

Moreira BG, You Y, Behlke MA, and Owczarzy R (2005) Effects of fluorescent dyes, quenchers, and dangling ends on DNA duplex stability. Biochem. Biophys. Res. Comm., 327: 473-484

Owczarzy R, You Y, Moreira B, Manthey JA, Huang L, Behlke MA, and Walder JA (2004) Effects of sodium ions on DNA duplex oligomers: Improved predictions of melting temperatures. Biochemistry, 43: 3537-3554

Owczarzy R, Dunietz I, Behlke MA, Klotz IM, and Walder JA (2003) Thermodynamic treatment of oligonucleotide duplex-simplex equilibria. Proc. Natl. Acad. Sci. USA, 100: 14840-14845

Full list of IDT Publications